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1

Mechanics and Single-Molecule Interrogation of DNA Recombination

Bell, Jason C., Kowalczykowski, Stephen C.

Journal:

Annual Review of Biochemistry

Year:

2016

Language:

english

File:

PDF, 2.59 MB

english, 2016

2

Independent and Stochastic Action of DNA Polymerases in the Replisome

Graham, James E., Marians, Kenneth J., Kowalczykowski, Stephen C.

Journal:

Year:

2017

Language:

english

File:

PDF, 6.70 MB

english, 2017

3

Visualizing protein–DNA interactions at the single-molecule level

Jovencio Hilario, Stephen C Kowalczykowski

Journal:

Current Opinion in Chemical Biology

Year:

2010

Language:

english

File:

PDF, 493 KB

english, 2010

4

Crystal structure of RecBCD enzyme reveals a machine for processing DNA breaks

Singleton, Martin R., Dillingham, Mark S., Gaudier, Martin, Kowalczykowski, Stephen C., Wigley, Dale B.

Journal:

Year:

2004

Language:

english

File:

PDF, 410 KB

english, 2004

5

A Molecular Throttle: The Recombination Hotspot χ Controls DNA Translocation by the RecBCD Helicase

Maria Spies, Piero R. Bianco, Mark S. Dillingham, Naofumi Handa, Ronald J. Baskin, Stephen C. Kowalczykowski

Journal:

Year:

2003

Language:

english

File:

PDF, 435 KB

english, 2003

6

Building a Better Engine: Stimulation of Single Molecules of SGS1 by RPA and Top3-RMI1

Bell, Jason C., Petr, Cejka, Stephen, Kowalczykowski C.

Journal:

Biophysical Journal

Year:

2014

Language:

english

File:

PDF, 42 KB

english, 2014

7

Watching Individual Molecules: Understanding Biology from Stochastic Behavior

Kowalczykowski, Stephen

Journal:

Biophysical Journal

Year:

2018

Language:

english

File:

PDF, 60 KB

english, 2018

8

Chi-activated RecBCD enzyme possesses 5′→3′ nucleolytic activity, but RecBC enzyme does not: evidence suggesting that the alteration induced by Chi is not simply ejection of the RecD subunit

Daniel G. Anderson, Jason J. Churchill, Stephen C. Kowalczykowski

Journal:

Year:

1997

Language:

english

File:

PDF, 997 KB

english, 1997

9

Essential monomer–monomer contacts define the minimal length for the N-terminus of RecA protein

Eugene N. Zaitsev, Stephen C. Kowalczykowski

Journal:

Molecular Microbiology

Year:

1998

Language:

english

File:

PDF, 89 KB

english, 1998

10

Enhanced monomer–monomer interactions can suppress the recombination deficiency of the recA142 allele

Eugene N. Zaitsev, Stephen C. Kowalczykowski

Journal:

Molecular Microbiology

Year:

1999

Language:

english

File:

PDF, 260 KB

english, 1999

11

The DNA binding and pairing preferences of the archaeal RadA protein demonstrate a universal characteristic of DNA strand exchange proteins

Erica M. Seitz, Stephen C. Kowalczykowski

Journal:

Molecular Microbiology

Year:

2000

Language:

english

File:

PDF, 118 KB

english, 2000

12

A distinctive single-stranded DNA-binding protein from the Archaeon Sulfolobus solfataricus

Cynthia A. Haseltine, Stephen C. Kowalczykowski

Journal:

Molecular Microbiology

Year:

2002

Language:

english

File:

PDF, 538 KB

english, 2002

13

A novel family of regulated helicases/nucleases from Gram-positive bacteria: insights into the initiation of DNA recombination

Frédéric Chédin, Stephen C. Kowalczykowski

Journal:

Molecular Microbiology

Year:

2002

Language:

english

File:

PDF, 389 KB

english, 2002

14

10.1038/34950

Kowalczykowski, Stephen C., New, James H., Sugiyama, Tomohiko, Zaitseva, Elena

Journal:

Year:

1998

Language:

english

File:

PDF, 331 KB

english, 1998

15

10.1038/35012652

Kowalczykowski, Stephen C., Bianco, Piero R.

Journal:

Year:

2000

Language:

english

File:

PDF, 286 KB

english, 2000

16

10.1038/35053131

Bianco, Piero R., Brewer, Laurence R., Corzett, Michele, Balhorn, Rod, Yeh, Yin, Kowalczykowski, Stephen C., Baskin, Ronald J.

Journal:

Year:

2001

Language:

english

File:

PDF, 350 KB

english, 2001

17

Cancer: Catalyst of a catalyst

Kowalczykowski, Stephen C.

Journal:

Year:

2005

Language:

english

File:

PDF, 2.53 MB

english, 2005

18

Structural biology: Snapshots of DNA repair

Kowalczykowski, Stephen C.

Journal:

Year:

2008

Language:

english

File:

PDF, 1.29 MB

english, 2008

19

10.1038/81923

Kowalczykowski, Stephen C.

Journal:

Natural Structural Biology

Year:

2000

Language:

english

File:

PDF, 83 KB

english, 2000

20

The Srs2 helicase prevents recombination by disrupting Rad51 nucleoprotein filaments

Veaute, Xavier, Jeusset, Josette, Soustelle, Christine, Kowalczykowski, Stephen C., Le Cam, Eric, Fabre, Francis

Journal:

Year:

2003

Language:

english

File:

PDF, 265 KB

english, 2003

21

RecBCD enzyme is a bipolar DNA helicase

Dillingham, Mark S., Spies, Maria, Kowalczykowski, Stephen C.

Journal:

Year:

2003

Language:

english

File:

PDF, 309 KB

english, 2003

22

Direct observation of individual RecA filaments assembling on single DNA molecules

Galletto, Roberto, Amitani, Ichiro, Baskin, Ronald J., Kowalczykowski, Stephen C.

Journal:

Year:

2006

Language:

english

File:

PDF, 386 KB

english, 2006

23

Purified human BRCA2 stimulates RAD51-mediated recombination

Jensen, Ryan B., Carreira, Aura, Kowalczykowski, Stephen C.

Journal:

Year:

2010

Language:

english

File:

PDF, 697 KB

english, 2010

24

DNA end resection by Dna2–Sgs1–RPA and its stimulation by Top3–Rmi1 and Mre11–Rad50–Xrs2

Cejka, Petr, Cannavo, Elda, Polaczek, Piotr, Masuda-Sasa, Taro, Pokharel, Subhash, Campbell, Judith L., Kowalczykowski, Stephen C.

Journal:

Year:

2010

Language:

english

File:

PDF, 463 KB

english, 2010

25

Molecular mimicry connects BRCA2 to Rad51 and recombinational DNA repair

Kowalczykowski, Stephen C.

Journal:

Natural Structural Biology

Year:

2002

Language:

english

File:

PDF, 587 KB

english, 2002

26

Rmi1 stimulates decatenation of double Holliday junctions during dissolution by Sgs1–Top3

Cejka, Petr, Plank, Jody L, Bachrati, Csanad Z, Hickson, Ian D, Kowalczykowski, Stephen C

Journal:

Nature Structural and Molecular Biology

Year:

2010

Language:

english

File:

PDF, 829 KB

english, 2010

27

Structure of the SWI2/SNF2 chromatin-remodeling domain of eukaryotic Rad54

Thomä, Nicolas H, Czyzewski, Bryan K, Alexeev, Andrei A, Mazin, Alexander V, Kowalczykowski, Stephen C, Pavletich, Nikola P

Journal:

Nature Structural and Molecular Biology

Year:

2005

Language:

english

File:

PDF, 913 KB

english, 2005

28

Rad52-mediated DNA annealing after Rad51-mediated DNA strand exchange promotes second ssDNA capture

Sugiyama, Tomohiko, Kantake, Noriko, Wu, Yun, Kowalczykowski, Stephen C

Journal:

The EMBO Journal

Year:

2006

Language:

english

File:

PDF, 434 KB

english, 2006

29

Single-molecule imaging of DNA pairing by RecA reveals a three-dimensional homology search

Forget, Anthony L., Kowalczykowski, Stephen C.

Journal:

Year:

2012

Language:

english

File:

PDF, 880 KB

english, 2012

30

Tailed duplex DNA is the preferred substrate for Rad51 protein-mediated homologous pairing

Mazin, Alexander V., Zaitseva, Elena, Sung, Patrick, Kowalczykowski, Stephen C.

Journal:

The EMBO Journal

Year:

2000

Language:

english

File:

PDF, 381 KB

english, 2000

31

RecA

Roberto Galletto, Stephen C. Kowalczykowski

Journal:

Current Biology

Year:

2007

Language:

english

File:

PDF, 385 KB

english, 2007

32

Single-molecule imaging brings Rad51 nucleoprotein filaments into focus

Anthony L. Forget, Stephen C. Kowalczykowski

Journal:

Trends in Cell Biology

Year:

2010

Language:

english

File:

PDF, 471 KB

english, 2010

33

Initiation of genetic recombination and recombination-dependent replication

Stephen C Kowalczykowski

Journal:

Trends in Biochemical Sciences

Year:

2000

Language:

english

File:

PDF, 297 KB

english, 2000

34

Tokio Kogoma (1939–1997)

Stephen Kowalczykowski, Peter von Hippel

Journal:

Trends in Biochemical Sciences

Year:

2000

Language:

english

File:

PDF, 47 KB

english, 2000

35

Novel homologs of replication protein A in Archaea: implications for the evolution of ssDNA-binding proteins

Frédéric Chédin, Erica M Seitz, Stephen C Kowalczykowski

Journal:

Trends in Biochemical Sciences

Year:

1998

Language:

english

File:

PDF, 922 KB

english, 1998

36

The Mutant recBCD Enzyme, recB2109CD Enzyme, Has Helicase Activity but Does Not Promote Efficient Joint Molecule Formation in Vitro

Angela K. Eggleston, Stephen C. Kowalczykowski

Journal:

Journal of Molecular Biology

Year:

1993

File:

PDF, 974 KB

1993

37

Biochemical Characterization of a Mutant recBCD Enzyme, the recB2109CD Enzyme, Which Lacks χ-specific, but Not Non-specific, Nuclease Activity

Angela K. Eggleston, Stephen C. Kowalczykowski

Journal:

Journal of Molecular Biology

Year:

1993

File:

PDF, 1.27 MB

1993

38

Negative Co-dominant Inhibition of recA Protein Function: Biochemical Properties of the recA1, recA13 and recA56 Proteins and the Effect of recA56 Protein on the Activities of the Wild-type recA Protein Function in Vitro

Scott D. Lauder, Stephen C. Kowalczykowski

Journal:

Journal of Molecular Biology

Year:

1993

File:

PDF, 1.51 MB

1993

39

SSB protein controls RecBCD enzyme nuclease activity during unwinding: a new role for looped intermediates

Daniel G Anderson, Stephen C Kowalczykowski

Journal:

Journal of Molecular Biology

Year:

1998

Language:

english

File:

PDF, 430 KB

english, 1998

40

The simultaneous binding of two double-stranded DNA molecules by Escherichia coli RecA protein

Eugene N Zaitsev, Stephen C Kowalczykowski

Journal:

Journal of Molecular Biology

Year:

1999

Language:

english

File:

PDF, 280 KB

english, 1999

41

The Bacillus subtilis AddAB helicase/nuclease is regulated by its cognate Chi sequence in vitro

Frédéric Chédin, S.Dusko Ehrlich, Stephen C Kowalczykowski

Journal:

Journal of Molecular Biology

Year:

2000

Language:

english

File:

PDF, 413 KB

english, 2000

42

A novel, 11 nucleotide variant of χ, χ∗: one of a class of sequences defining the Escherichia coli recombination hotspot χ

Deana A Arnold, Naofumi Handa, Ichizo Kobayashi, Stephen C Kowalczykowski

Journal:

Journal of Molecular Biology

Year:

2000

Language:

english

File:

PDF, 281 KB

english, 2000

43

Archaeal RadA protein binds DNA as both helical filaments and octameric rings

Shixin Yang, Xiong Yu, Erica M Seitz, Stephen C Kowalczykowski, Edward H Egelman

Journal:

Journal of Molecular Biology

Year:

2001

Language:

english

File:

PDF, 432 KB

english, 2001

44

Rad54 protein stimulates heteroduplex DNA formation in the synaptic phase of DNA strand exchange via specific interactions with the presynaptic Rad51 nucleoprotein filament

Jachen A Solinger, Géraldine Lutz, Tomohiko Sugiyama, Stephen C Kowalczykowski, Wolf-Dietrich Heyer

Journal:

Journal of Molecular Biology

Year:

2001

Language:

english

File:

PDF, 394 KB

english, 2001

45

RecBCD Enzyme Switches Lead Motor Subunits in Response to χ Recognition

Maria Spies, Ichiro Amitani, Ronald J. Baskin, Stephen C. Kowalczykowski

Journal:

Year:

2007

Language:

english

File:

PDF, 1.12 MB

english, 2007

46

The BRC Repeats of BRCA2 Modulate the DNA-Binding Selectivity of RAD51

Aura Carreira, Jovencio Hilario, Ichiro Amitani, Ronald J. Baskin, Mahmud K.K. Shivji, Ashok R. Venkitaraman, Stephen C. Kowalczykowski

Journal:

Year:

2009

Language:

english

File:

PDF, 1.59 MB

english, 2009

47

A RecA Mutant, RecA730, Suppresses the Recombination Deficiency of the RecBC1004D–χ* Interaction in Vitro and in Vivo

Naofumi Handa, Stephen C. Kowalczykowski

Journal:

Journal of Molecular Biology

Year:

2007

Language:

english

File:

PDF, 1.04 MB

english, 2007

48

The RecA Binding Locus of RecBCD Is a General Domain for Recruitment of DNA Strand Exchange Proteins

Maria Spies, Stephen C. Kowalczykowski

Journal:

Year:

2006

Language:

english

File:

PDF, 407 KB

english, 2006

49

Visualization of Rad54, a Chromatin Remodeling Protein, Translocating on Single DNA Molecules

Ichiro Amitani, Ronald J. Baskin, Stephen C. Kowalczykowski

Journal:

Year:

2006

Language:

english

File:

PDF, 269 KB

english, 2006

50

The Recombination Hot Spot Chi Is Embedded within Islands of Preferred DNA Pairing Sequences in the E. coli Genome

Robert B Tracy, Frédéric Chédin, Stephen C Kowalczykowski

Journal:

Year:

1997

Language:

english

File:

PDF, 101 KB

english, 1997